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Anti-VEGF treatment for wet AMD may hasten progression of glaucoma

Glaucoma patients who receive anti-VEGF injections for treatment of Neovascular age-related macular degeneration (nAMD) are at a higher risk of their glaucoma getting worse.

Researchers wanted to know how frequently glaucoma and nAMD

occur in the same patient and whether glaucoma progresses more quickly with anti-VEGF treatments.

Patient medical records from Tays Eye Center were reviewed and involved 6,314 glaucoma and 2,166 nAMD patients. Researchers discovered that the progression of glaucoma was found in 14 of 20 vs 10 of 20 fundus photographs in eyes with anti-VEGF treatment compared to patients with untreated eyes.

Researchers concluded that anti-VEGF treatments do raise the risk of glaucoma progression but also note that anti-VEGF treatment occurred in combination with glaucoma at the same rate as in the general population.

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