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VisiVite Blue Light Basher with Lutein Formula

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Specific plant pigments depower high-energy ultraviolet and blue light. VisiVite Blue Light Basher harnesses that natural method by providing our bodies with lutein, zeaxanthin, and 7 additional rich-colored plant pigments that are known to replenish the macular pigment layer of the retina and manage high energy blue light, thereby providing unique nutritional support for both the eyes and skin.

High energy blue light is everywhere - cell phones, TV’s, LED lights and sunlight itself. Too much exposure to blue light can lead to digital eyestrain and damage to retinal cells. VisiVite Blue Light Basher with Lutein and 8 additional targeted ingredients uniquely replenishes the macular pigment layer and adds additional ingredients that absorb and dissipate high energy blue light in nature.

blue light computer

What is Blue Light?

High energy blue light is visible and directly next to ultraviolet on the light spectrum. In other words, it’s the first high-energy light in the light spectrum that we are able to see, and it’s only a few wavelengths away from ultraviolet light. Blue light has a wavelength between 400-450 nanometers, whereas UV light spans from 100-400 nanometers.

light wavelengths

Blue light is of concern because it has more energy per photon of light than other colors in the visible spectrum, i.e. green or red light. Blue light, at high enough doses, is therefore more likely to cause damage when absorbed by various cells in our body.

 

Where is Blue Light?

Sunlight contains blue light, but because it contains a mixture of the complete spectrum of visible colors, we don’t perceive the light as being blue.

LED lights, televisions and computers, on the other hand, emit more blue light than traditional light sources. Blue light can stimulate your biological circadian clock, keeping you awake, disrupting sleep, or having adverse effects on your circadian rhythm.

 

Does Blue Light Cause Eye Damage?

There are no studies showing that blue light from electronic devices causes macular degeneration.

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However, there are studies in the laboratory showing that blue light can cause cellular damage, either directly to retinal cells or to the supporting retinal pigment epithelial cells directly below the retina.

 

How does Nature Protect Itself against Blue Light?

Fortunately, the plant world, exposed to all-day light from the sun, has already developed mechanisms for protecting itself against high energy light, including Ultraviolet A, B and C, as well as blue light. And the answer is in the antioxidant properties of its colorful pigments, including lutein.

Plant Pigment Wavelength Absorption

 

These pigments not only help to absorb light and convert it to food and energy that the plant can use, but because there is in many cases an excess of light energy required for growth, the pigment also has the ability to dissipate the high energy light that can activate unstable forms of oxygen, which cause damage from “oxidation.”




In developing VisiVite Blue Light Basher with lutein, Dr. Krawitz and our nutritional scientists utilized the colorful pigments that were already successful in the plant world to manage high energy light waves.

 

Blue Light Basher Ingredients Include:

Lutein 10 mg and Zeaxanthin 2 mg

The carotenoids lutein and zeaxanthin are plant-derived pigments. Because these carotenoids absorb visible light and are incorporated into ocular tissues, they can influence the optical characteristics of the human eye. The yellow-orange color of carotenoids has been shown to build healthy macular pigment optical density (MPOD) which then selectively absorbs the shorter wavelengths of the visible spectrum from 400–500 nm, with a peak absorbance of blue light at 460 nm). Blue light is thus filtered, with studies showing improvement in contrast and glare recovery. Studies have also shown that two of the major mechanisms of protection offered by lutein and zeaxanthin against age-related blue light damage are the quenching of singlet oxygen and other reactive oxygen species and the absorption of blue light.

Lycopene 2 mg
Lycopene is the major carotenoid of the tomato and is a very efficient singlet oxygen quencher in the group of carotenoids. Following ingestion of lycopene or tomato-derived products rich in lycopene, photoprotective effects have been demonstrated. Lycopene has a stronger singlet oxygen-quenching capacity (antioxidant activity) than several carotenoids, including lutein.

Astaxanthin 1 mg
Astaxanthin is a red-colored, xanthophyll carotenoid that occurs in trout, microalgae, yeast, and shrimp, among other sea creatures. Plants and living creatures with a red color are even more susceptible to blue light damage than those which are green. Research also suggests that some organisms secrete astaxanthin in response to intense light to prevent cell death.

Red beet root extract 50 mg
Betanin is one example of a betalain, and is the main pigment found in red beet, and studies show it has radical scavenging properties for protection against certain oxidative stress-related disorders. Studies suggest that betalains are more stable and less prone to oxidative damage than anthocyanidins. Betanin preferentially absorbs light in in the yellow, green, ultraviolet and blue wavelengths.(280–400nm and 500 – 550 nm).

Turmeric 40 mg
Turmeric is a bright orange spice containing the active compound curcumin. Given orally, this compound has long been studied for its ability to address cellular irritation and the subsequent tissue changes that can result. Recent research also points to its ability to work topically in burns and as eyedrops for glaucoma. While the extent and mechanism of blue light effect are not yet completely understood, one theory is that oxidative stress from the high energy wavelength is ultimately followed by an inflammatory cascade, releasing a variety of pro-inflammatory factors, including tumor necrosis factor (TNF) and IL-1. These mechanisms may be responsible for lower cell death seen in cultured cell studies.

Chlorphyll 50 mg
Chlorophyll's absorption of blue light, and to a lesser extent red light, is what gives the leaves of many plants their green color. In addition to its important function in photosynthesis, chlorophyll also performs the critically important activity of dissipating the sun's energy so that intense light and oxidative damage do not burn and kill the leaves. Chlorophyll is nature's method of dissipating high-energy light energy, including Ultraviolet (UV-A 315 – 400 nm, UV-B 280 – 315 nm, and UV-C 100 – 280 nm) and blue light (380 - 500 nm). Chlorophyll acts as a light quencher, which protects the plant; and its ability to avoid degradation is facilitated by carotenoids, such as lutein, zeaxanthin and astaxanthin.

Bilberry 50 mg
Bilberry has been studied primarily in its ability to foster healthy circulation of blood to the small vessels feeding the eye. But in animal and tissue samples, research also shows that bilberry reduces cell destruction in response to blue and other high energy light wavelengths in the retinal photoreceptor layer and underlying retinal pigment epithelial cells. Its mechanism appears to reduce the formation of reactive oxygen species, and thus act against oxidative stress.

Zinc 10 mg
Zinc is involved in numerous aspects of cellular metabolism. It is required for the catalytic activity of approximately 100 enzymes, and it plays a role in immune reactivity, the formation of proteins, wound healing, DNA formation and cell division. Studies now also support zinc's role in protecting the eyes due to strong light exposure.

Blue Light References

A Double-Blind, Placebo-Controlled Study on the Effects of Lutein and Zeaxanthin on Photostress Recovery, Glare Disability, and Chromatic Contrast. Billy R. Hammond; Laura M. Fletcher; Franz Roos; Jonas Wittwer; Wolfgang Schalch. Investigative Ophthalmology & Visual Science December 2014, Vol.55, 8583-8589.
Conclusions: Daily supplementation with 10 mg lutein and 2 mg zeaxanthin resulted in significant increase in serum levels and MPOD and improvements in chromatic contrast and recovery from photostress. These results are consistent with past studies showing that increasing MPOD leads to improved visual performance.

The glare hypothesis of macular pigment function. Stringham JM, Hammond BR. Optom Vis Sci. 2007 Sep;84(9):859-64.
Conclusions: Macular Pigment was found to dramatically reduce the deleterious effects of glare. Visual thresholds under glare conditions were strongly related to macular pigment density. Photostress recovery time, after exposure to xenon-white light, was significantly shorter for subjects with higher macular pigment levels. Both photostress recovery and veiling glare functions were well-described by the photopic spectral sensitivity function.

Macular pigment and visual performance under glare conditions. Stringham JM, Hammond BR. Optom Vis Sci. 2008 Feb;85(2):82-8.
Conclusions: Macular Pigment is strongly related to improvements in glare disability and photostress recovery in a manner strongly consistent with its spectral absorption and spatial profile. Four to 6 months of 12 mg daily lutein plus zeaxanthin supplementation significantly increases Macular Pigment Optical Density (MPOD) and improves visual performance in glare for most subjects.

The Photobiology of Lutein and Zeaxanthin in the Eye.Roberts JE, Dennison J. J Ophthalmol. 2015;2015:687173.
Findings: Lutein and zeaxanthin are antioxidants found in the human retina and macula. Recent clinical trials have determined that age- and diet-related loss of lutein and zeaxanthin enhances phototoxic damage to the human eye and that supplementation of these carotenoids has a protective effect against photoinduced damage to the lens and the retina.

Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells. Bian Q, Gao S, Zhou J, Qin J, Taylor A, Johnson EJ, Tang G, Sparrow JR, Gierhart D, Shang F. Free Radic Biol Med. 2012 Sep 15;53(6):1298-307.
Findings: Protecting the proteasome from oxidative inactivation appears to be one of the mechanisms by which lutein and zeaxanthin modulate the inflammatory response. Similar mechanisms may explain salutary effects of lutein and zeaxanthin in reducing the risk for AMD.

Lycopene-rich products and dietary photoprotection. Wilhelm Stahl, Ulrike Heinrich, Olivier Aust, Hagen Tronnierb and Helmut Sies. Photochemical & Photobiological Sciences.2006,5, 238-242.
Findings: Dietary carotenoids may contribute to life-long protection against harmful UV radiation.

Lycopene and Lutein; A review for their Chemistry and Medicinal Uses. Mohamed A. El-Raey, Gamil E. Ibrahim2, Omayma A. Eldahshan. Journal of Pharmacognosy and Phytochemistry. Vol. 2 No. 1 2013
Findings: The many conjugated double bonds of carotenoids make them potentially powerful antioxidants. Lycopene had the strongest singlet oxygen-quenching capacity of several carotenoids, with α-carotene, ß-carotene, and lutein next in capacity. The weakest singlet oxygen quencher of the antioxidants studied was α-tocopherol, which is found in much greater concentrations in many body systems.

The Protective Effects of a Dietary Carotenoid, Astaxanthin, Against Light-Induced Retinal Damage. Tomohiro Otsuka, Masamitsu Shimazawa, Tomohiro Nakanishi, Yuta Ohno, Yuki Inoue, Kazuhiro Tsuruma, Takashi Ishibashi, Hideaki Hara. Journal of Pharmacological Science.
Findings: Astaxanthin has protective effects against light-induced retinal damage via the mechanism of its antioxidative effect.

Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review. Ranga Rao Ambati, Phang Siew Moi, Sarada Ravi, and Ravishankar Gokare Aswathanarayana. Marine Drugs 2014, 12, 128-152.
Findings: Astaxanthin, used as a nutritional supplement, antioxidant and anticancer agent, supports diabetes control, cardiovascular diseases, and neurodegenerative disorders, and also stimulates immunization.

Does Astaxanthin Protect Haematococcus against Light Damage? Avigad Vonshak, Aliza Zarka, Sammy Boussiba .Biosciences, Volume 53, Issue 1-2, Pages 93–100
Findings: When exposed to high irradiance and/or nutritional stress, green Haematococcus cells turned red due to accumulation of an immense quantity of the red pigment astaxanthin. The addition of diphenylamine, an inhibitor of astaxanthin biosynthesis, causes cell death under high light intensity.

Betanin, the main pigment of red beet: Molecular origin of its exceptionally high free radical-scavenging activity. H. Szymusiak, P. Malinowska.
Findings: The exceptionally high antioxidant activity of betanin is associated with an increasing of its H-donation and electron-donation ability when going from cationic state to mono-, di- and tri-deprotonated states present at basic solutions.

Recent advances in betalain research. Strack D1, Vogt T, Schliemann W. Phytochemistry. 2003 Feb;62(3):247-69.
Findings: Betalains have attracted workers in applied fields because of their use for food colouring and their antioxidant and radical scavenging properties for protection against certain oxidative stress-related disorders.

Topical Curcumin Nanocarriers are Neuroprotective in Eye Disease. Davis et al. Scientific Reports volume 8, Article number: 11066 (2018)
Findings: Topical application of curcumin-loaded nanocarriers twice-daily for three weeks significantly reduced retinal ganglion cell loss compared to controls.

Phosphorylase Kinase Inhibition Therapy in Burns and Scalds. Hang, M. BioDiscovery 20: 11207.
Findings: use of curcumin after burns and scalds were found to reduce the severity of the injury, lessen pain and redness, and improve healing with less than expected scarring, or even no scarring, of the affected skin.

Research progress about the effect and prevention of blue light on eyes. Zhi-Chun Zhao,Ying Zhou, Gang Tan,and Juan Li. International Journal of Ophthalmology, 2018; 11(12): 1999–2003.
Findings: In the visible spectrum, short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration, even stimulating the brain, inhibiting melatonin secretion, and enhancing adrenocortical hormone production.

Anti‐apoptotic effects of Curcuma longa L. extract and its curcuminoids against blue light‐induced cytotoxicity in A2E‐laden human retinal pigment epithelial cells. Sang‐il Park, Eun Hye Lee, So Ra Kim, Young Pyo Jang. Journal of Pharmacy and Pharmacology, Feb 2017.
Findings: Curcumin, demethoxycurcumin and bisdemethoxycurcumin exerted significant protective effects against blue light‐induced cytotoxicity.

ENERGY DISSIPATION AND PHOTOPROTECTION MECHANISMS DURING CHLOROPHYLL PHOTOBLEACHING IN THYLAKOID MEMBRANES. Nathalie Miller, Robert Carpentier. Photochemistry and PhotobiologyVolume 54, Issue 3, September 1991.
Findings: Chlorophyll photobleaching acts as an energy trap for the photoprotection affecting blue and red wavelengths.

Nonphotochemical Chlorophyll Fluorescence Quenching: Mechanism and Effectiveness in Protecting Plants from Photodamage. Alexander Ruban. Plant Physiology, April 2016.
Findings: Photochemical chlorophyll fluorescence quenching plays a critical role in protecting plants against photoinhibition.

Role of Carotenoids in Protecting Chlorophyll From Photodestruction. I.C. Anderson, D.S. Robertson. Plant Physiology, 1960 Jul 35(4): 531-534
Findings: Pigmented carotenoids work to prevent the photodestruction of chlorophyll pigment.

Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro. Ogawa K, Kuse Y, Tsuruma K, Kobayashi S, Shimazawa M, Hara H. BMC Complement Altern Med. 2014 Apr 2;14:120.
Findings: Bilberry and Lingonberry extracts and their active components improved the viability of photoreceptor cells and inhibited the generation of intracellular reactive oxygen species induced by blue LED light irradiation. Furthermore, these extrats inhibited the activation of protein kinase induced by blue LED light exposure and autophagy of cells.

Polyphenol-enriched Vaccinium uliginosum L. fractions reduce retinal damage induced by blue light in A2E-laden ARPE19 cell cultures and mice. Bob-Lee Lee et al. Nutrition Research, Vol 36, Issue 12, December 2016.
Findings: Bilberry extract fractions and constituent compounds significantly reduced photo-oxidation–induced retinal pigment epithelial cell death and inhibited intracellular lipofuscin accumulation.

Light-Induced Retinal Degeneration Is Prevented by Zinc, a Component in the Age-related Eye Disease Study Formulation. Daniel Organisciak et al. Photochem Photobiol. 2012 Nov-Dec; 88(6): 1396–1407.
Findings: Zinc oxide treatment effectively prevented retinal light damage as determined by rhodopsin and retinal DNA recovery, histology and electrophoretic analysis of DNA damage and oxidized retinal proteins.

 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

VisiVite Advantage

VisiVite Eye Vitamin Formulas are based on proven research in the most respected medical publications, including the National Eye Institute's Age-Related Eye Disease Study (AREDS) Age-Related Eye Disease Study 2 (AREDS2), the Lutein Antioxidant Supplement Trial (LAST) and others. 

Quality Control

VisiVite eye vitamins source FloraGLO brand lutein, OmniXan brand zeaxanthin and Natural Vitamin E from plant oils, which are then assembled in a climate-controlled GMP-certified facility.  Independent third party laboratories analyze the finished products for potency and purity.

Dr. Paul Krawitz

Dr. Paul Krawitz is a Magna Cum Laude graduate of The University of Michigan, and received his medical degree in 1985. He is a member of the prestigious Alpha Omega Alpha Medical Honor Society.

Dr. Krawitz trained in Internal Medicine at Columbia-Presbyterian Hospital, New York. He completed his Ophthalmology training at Mount Sinai Medical Center, New York, and later was selected as Chief Resident of that program.

He completed an additional year of specialized fellowship training in Glaucoma at Mount Sinai under the direction of Steven Podos, a recognized world leader in that field.

Dr. Krawitz holds the academic position of Assistant Clinical Professor of Ophthalmology in Manhattan. He is a frequent lecturer at professional ophthalmic meetings regarding his highly successful surgical techniques for cataracts, glaucoma and specialty intraocular lenses.

In his position as President and C.E.O. of Vitamin Science, Inc., Dr. Krawitz holds several patents and trademarks for nutritional supplements that treat eye disease.

He is a physician partner of OCLI - Ophthalmic Consultants of Long Island - one of the leading eye care practices in the United States. Since 1993, he has become one of Long Island's most highly sought and professionally recognized eye surgeons. Dr. Krawitz performs over 1000 ophthalmic procedures annually, including no-stitch cataract surgery, the most modern therapies for glaucoma, laser refractive surgery, and laser treatment of both macular degeneration and diabetic retinopathy.

Dr. Krawitz is a Diplomate of The American Board of Ophthalmology and a Fellow of The American Academy of Ophthalmology. He is an active member of the Long Island Ophthalmologic Society, The Suffolk Academy of Medicine, and the American Medical Association.

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09/03/2020
Frank C.
United States United States
First time user -

A new user. Need to give it time. Users of their others eye products for my husband for over 10 years. Thanks

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