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Do Eye Vitamins Help?

The Story of VisiVite Eye Vitamins

Most people consider their eyesight priceless. But the sad fact is that loss of vision due to degenerative diseases of the eye, especially macular degeneration, occur to thousands of people daily. In fact, macular degeneration is the most common cause of irreversible blindness in the Western world.

And it wasn't long ago that nothing seemed to work. Not vitamins. Not laser. Not medications.

But on an October afternoon in 2001, all ophthalmologists in the United States received an "Urgent Message" over their fax machines from the National Eye Institute. The news was a revelation:

"Study shows benefit of high dose nutritional supplements in slowing macular degeneration."

Now, if you were a layperson, you might not have the same reaction as ophthalmologists did. We, on the other hand were surprised and delighted. You see, there had been many studies before, and certainly many supplements already existed on drugstore shelves. But the sad fact is that none of them worked. So we couldn't help but feel jaded and pessimistic about the future of "eye vitamins."

But we never received a fax like this before. And it was from the National Eye Institute, part of the United States Government's National Institutes of Health, the most revered scientific institution in the nation.

The study was impressive in that it studied thousands of patients. And it was well designed, with placebo treatments and both patient and doctor being "blind" to which pill the patient was receiving.

But the message was clear: Take this very, very high dose supplement as outlined in AREDS (Age Related Eye Disease Study) , and the chances of vision loss due to macular degeneration were reduced.

One week after the AREDS results were published, I filed corporate papers for Vitamin Science Inc and began the web site VisiVite.Com. It was the absolute infancy of the Internet. But we had our first product, VisiVite Original AREDS Formula.

visivite original areds formula
Original Formula duplicated the Anti-Oxidants and Zinc used in the National Institutes of Health AREDS Study for patients with Macular Degeneration. It was designed for non-smokers that had minimal macular degeneration with no vision loss.


Early on, it became my passion and that of the team that I surrounded myself with, to construct our supplements using only the country's premium laboratories, and to use safe natural ingredients whenever possible. Our first step toward fulfilling this mission was using Natural Vitamin E rather than Synthetic Vitamin E. Don't know the difference? Natural Vitamin E comes from plant oils, and contains only the letter "D" in the chemical name, whereas Synthetic Vitamin E contains the two letters, "DL" in the chemical name.

But there was a huge, glaring problem with VisiVite Original AREDS Formula.

It contained beta-carotene, a form of Vitamin A with powerful antioxidant properties. And although beta-carotene has beneficial effects in most people, two large studies showed it was dangerous in a particular group of people - smokers - and that taking high doses of beta-carotene not only was not helpful, it increased the risk of lung cancer.

At the time, I spoke with several scientists and nutritionists, and researched alternatives for a vitamin that would be safe for smokers. Soon, we had launched VisiVite Smokers Formula, which substituted Lutein, another carotenoid, for beta-carotene. Although we were the first company in the world, and for nearly two years the only company in the world to offer a smokers formula for the treatment of macular degeneration, several companies soon copied our idea and formula.

visivite smokers formulaVisiVite Smokers Formula was a basic formula for macular nutrition in smokers and former habitual smokers that had minimal macular degeneration and no vision loss. It was based on AREDS but with 8 mg of Lutein substituted in place of Beta-carotene.


The next step in our evolution was the continued study of the benefits of Lutein and Zeaxanthin. Although we had included Lutein in our VisiVite Smokers Formula merely to substitute for beta-carotene, the Lutein Antioxidant Supplementation Trial showed that Lutein could actually improve vision in people with dry macular degeneration. And several studies of Zeaxanthin, a compound closely related to Lutein, actually improved color and pigmentation in the retina and might be the most powerful carotenoid available.

In early 2003, we brought to market what was then considered by many of the country's ophthalmologists to be the most advanced formula for the treatment of macular degeneration, VisiVite Plus Formula. It contained the AREDS ingredients, but then added Lutein, Bilberry and Selenium. This formula later evolved into VisiVite i-Defense Gold Formula (for non-smokers) and VisiVite i-Defense Green Formula (for smokers and former habitual smokers). These formulas each contained 15 mg of Lutein and 4.75 mg of Zeaxanthin. The levels of Zeaxanthin that we offered, and still offer in these formulas, were more than 500% higher than other manufacturers. But the science proved what we suspected - the levels of these two compounds were critical to their success in supporting eyes with macular degeneration and in nourishing healthy vision.

i-Defense Gold
VisiVite i-Defense Gold Formula was a powerful macular degeneration product for non-smokers. Based on AREDS but with 15 mg of FloraGLO Lutein and 4.75 mg of OPTISHARP brand Zeaxanthin added, as well as Bilberry, L-glutathione, Selenium, Alpha Lipoic Acid and Grape Seed Extract. Less Zinc for easier tolerability. Best formula for people with moderate vision loss, wet macular degeneration in one eye as nutritional support for the remaining sighted eye, or for those people with milder disease who want the most advanced formula based on the latest scientific research.
i-defense green
VisiVite i-Defense Green Formula was a powerful macular degeneration nutritional formula for smokers and former habitual smokers. It was based on AREDS but with 15 mg of FloraGLO Lutein and 4.75 mg of OPTISHARP brand Zeaxanthin added, as well as Bilberry, L-glutathione, Selenium, Alpha Lipoic Acid and Grape Seed Extract. Less Zinc for easier tolerability. This product contained no beta-carotene. Designed for smokers with moderate vision loss, wet macular degeneration in one eye as protection for the remaining sighted eye, or for those people with milder disease who want the most advanced smokers formula based on the latest scientific research.


In fact, we spoke in 2003 with some of the AREDS investigators about visual improvement that we were witnessing with these two premium formulas and were told that the AREDS research never looked at the "bad eyes with bad vision," but only looked to prevent vision loss in the "good eyes."

The National Eye Institute followed up on AREDS  with the Age-Related Eye Disease Study 2, also known as AREDS 2, which then demonstrated the benefit and safety of lutein and zeaxanthin.

Lutein and Zeaxanthin, in particular, are very expensive. In fact some manufacturers advertise their Zeaxanthin levels of 500 mcg (micrograms) while we list it as mg's (milligrams). So although 500 mcg might seem like a lot of Zeaxanthin, it is only 10.5% as much Zeaxanthin as is now found in our VisiVite Gold Formula.

VisiVite E-Free Formula was then introduced specifically because people who take blood thinners were often advised by their doctors to not take Vitamin E. Creating this unique formula assuaged the fear of many internists and family practitioners who might otherwise have recommended their patients not take an AREDS-like supplement.

VisiVite i-Defense E-Free Formula for eye health  VisiVite i-Defense E-Free Formula was a powerful macular degeneration supplement available for patients that preferred to avoid high doses of Vitamin E either because of anticoagulation therapy or other reasons. Contained 20 mg FloraGLO brand Lutein, 4.75 mg OPTISHARP brand Zeaxanthin, 80 mg Zinc Oxide and many other anti-oxidants. This product contained no beta-carotene. This product is now available as VisiVite AREDS 2 E-Free Blue Formula.


What else makes VisiVite special?

The staff at Vitamin Science Inc. share the singular vision that VisiVite products must be considered to be the world's leader for quality and distinction. We trust our GMP certified laboratories, but nevertheless send our supplements to be independently measured for purity and potency each and every time a new manufacturing lot is produced. Our customer service staff is second to none, and can answer even the most complex nutritional questions that our customers have.

Doctors are delighted with the quality and the benefit to their patients in obtaining the correct supplement at a fair price. And they are reassured by our use of natural ingredients and independent laboratory testing of our products.

Dr. Paul Krawitz

Dr. Paul Krawitz, President and CEO
Vitamin Science, Inc.

Information on VisiVite.Com is for informational purposes for the general public only and cannot replace the recommendations and guidance of an eye care professional. Regular eye examinations are imperative to diagnose and treat real eye health issues.

Like all nutritional supplements, we are required by law to state the following:
Both our former and current products are not intended to diagnose, treat, cure or prevent any disease.

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